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E3 ligase Ligand-Linker Conjugates 9

" in MedChemExpress (MCE) Product Catalog:

5

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1

Click Chemistry

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-103606

    VH032-PEG6-C4-Cl; VHL Ligand-Linker Conjugates 10; E3 ligase Ligand-Linker Conjugates 9

    E3 Ligase Ligand-Linker Conjugates Cancer
    (S,R,S)-AHPC-PEG6-C4-Cl is a conjugate of ligands for E3 and 25-atom-length linker. The connector of linker is Halogen group. (S,R,S)-AHPC-PEG6-C4-Cl incorporates the (S,R,S)-AHPC based VHL ligand and 6-unit PEG linker. (S,R,S)-AHPC-PEG6-C4-Cl is capable of inducing the degradation of GFP-HaloTag7 in cell-based assays .
    (S,R,S)-AHPC-PEG6-C4-Cl
  • HY-41549

    Cereblon Ligand-Linker Conjugates 9; E3 ligase Ligand-Linker Conjugates 2

    E3 Ligase Ligand-Linker Conjugates Cancer
    Pomalidomide-PEG4-Ph-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and 4-unit PEG linker used in PROTAC technology.
    Pomalidomide-PEG4-Ph-NH2
  • HY-103600

    VH032-PEG1-N3; VHL Ligand-Linker Conjugates 9; E3 ligase Ligand-Linker Conjugates 3

    E3 Ligase Ligand-Linker Conjugates Cancer
    (S,R,S)-AHPC-PEG1-N3 is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and 1-unit PEG linker used in PROTAC technology. (S,R,S)-AHPC-PEG1-N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
    (S,R,S)-AHPC-PEG1-N3
  • HY-128824

    E3 ligase Ligand-Linker Conjugates 45

    E3 Ligase Ligand-Linker Conjugates Cancer
    cIAP1 Ligand-Linker Conjugates 9 incorporates an IAP ligand for the E3 ubiquitin ligase, and a PROTAC linker. cIAP1 Ligand-Linker Conjugates 9 can be used to design SNIPERs .
    cIAP1 Ligand-Linker Conjugates 9
  • HY-162183

    Ligands for E3 Ligase Autophagy Cancer
    E3 Ligase Ligand-linker Conjugate 9 is a conjugate of E3 ligase ligand and linker, consisting of Thalidomide (HY-14658) and the corresponding Linker. E3 Ligase Ligand-linker Conjugate 9 can serve as a Cereblon ligand to recruit CRBN protein and serve as a key intermediate for the synthesis of complete PROTAC molecules.
    <em>E3</em> <em>Ligase</em> <em>Ligand-linker</em> <em>Conjugate 9</em>

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